Botanical Name(s):
Thippali Family Name:
Piperaceae Kingdom: Plantae Division:
Magnoliophyta Class:
Magnoliopsida Order: Piperales Family:
Piperaceae Genus: Piper Species: P.
longum Popular Name(s):
Indian Thippali,
Indonesian Thippali,
Dried Catkins, Pippali,
Pipal, Tippli, Pihal,
Javanese Thippali Parts Used:
Fruit, Root and Stem. Habitat: Mostly
deciduous to evergreen
forests.
Description
Thippali is a
slender aromatic
climber, with a
large perennial
woody root and
jointed stems
thickening at the
nodes. The dark,
dentate leaves are
ovate and
heart-shaped, about
2 to 3 inches in
length, with broad
rounded lobes at the
base. The flowers
are monoceous and
male and female
flowers are borne on
different plants.
The fruits are
ovoid,
yellowish-orange,
minute, and drupe
around 1 inch in
diameter. The spikes
are red when ripe
and turn to black on
drying. The plant
bears flowers in
rains and fruits in
early winters. The
herb is cultivated
in Assam, Tamil Nadu
and Andhra Pradesh
in India, Malaysia,
Indonesia,
Singapore, Sri Lanka
and South Asian
regions. Thippali is
also known as pipal
and pipar in Hindi,
hippali in Kannada,
kandanthippili in
Tamil, pippali
rasayana, magadhi,
kana and ushana in
Sanskrit, pippal in
Gujarati and pepe di
Marisa in Italian.
About the plant
Thippali belongs to
the family of black
pepper, Piperaceae.
The plant is a
slender, glabrous,
climber or creeping
shrub that spreads
on ground striking
roots at each node.
It produces two
distinct dimorphic
branches –
vegetative main
branches that creep
on ground; and erect
growing reproductive axillary branches.
The plant flowers
through out the year
and is dioecious in
nature with the male
and female flowers
produced on
different plants.
Inflorescence is
spike; about 35
millimetres long and
5 millimetres thick,
composed of large
numbers of minute
grayish green or
darker grey fruits,
which, together with
the bracts that
support them, are
embedded in the
elongated axis; and
the the whole being
covered with greyish
dust.
Cultivation
Soil and climate
Thippali grows well
in organic matter
rich fertile,
well-drained soils.
Laterite soils with
high organic matter
content and moisture
holding capacity are
also suitable for
the cultivation.
Optimum elevation
for its cultivation
is between 100 to
1000 m and higher
elevations are not
conducive to high
yields. Partial
shade of 20-25 per
cent shade intensity
is found to be the
optimum.
Varieties
Different types of
thippali -
cheemathippali,
cheru thippali,
vanthippali, kattu
thippali are
identified.
Cheemathipali is a
common cultivated
clone of Kerala.
Viswam is a high
yielding variety of
thippali released by
the Kerala
Agricultural
University for
commercial
cultivation.
Nursery
preparation
Thippali is
propagated by rooted
vine cuttings or
suckers. Vine
cuttings of 3-5
nodes are planted in
polybags filled with
top soil, farm yard
manure and sand in
the ratio 1:1:1
during March-April.
Normal irrigation
may be given on
alternate days.
Excess moisture in
the nursery can
cause Phytophthora
wilt. To avoid
mealy-bug attack on
roots, 10 per cent
DP of any organo-phosphorus
insecticide is to be
mixed with the
potting mixture.
Cuttings will root
in two weeks and can
be transplanted to
the main field after
one month.
Land preparation
and sowing
The field should be
ploughed two to
three times and
levelled properly.
Raised beds of size
3m x2.5 m are
prepared and pits
are dug at a
distance of 60 cm x
60 cm. Dried cow
dung or farmyard
manure at the rate
of 100 g per pit is
applied and mixed
with soil.
Application of
chemical fertilizers
is not practiced
commonly. Plant two
rooted cuttings or
suckers per pit in
the main field soon
after the onset of
monsoon.
Main constituents
The chief
constituents of
thippali are about
six per cent of
piperine and one per
cent of volatile
oil. Other
constituents are a
pungent resin namely
chavicin and starch.
Compounds like piper
longuminine,
cetostearol, methyl
piperate and a
series of piperine
retrofractamides
have also been
reported.
Habitat
It is considered a
native of South Asia
and is found both
wild as well as
cultivated,
throughout the
hotter parts of
India from central
to the north-eastern
Himalayas. The herb
also grows wild in
Malaysia, Singapore,
Bhutan, Myanmar and
elsewhere.
What Ayurveda has to
say on Thippali:
It suppresses the
influence of peta
body type and
enhances the role of
vata and kapha body
types. This restores
balance among the
basic body types.
Its pungent taste
is believed by Ayurveda to treat
any kind of
infection.
Its treats asthma
by clearing the
mucus which get
stuck in the
pathways of
breathing.
It clears pathways
from where food
passes and gets
converted in to
waste products. In
this way,
constipation is
addressed.
It is believed to
treat Sinus problem
and nervous weakness
too.
Oil prepared from
extracts of the
fruits of this herb
are applied on the
wounds to treat
them.
The roots are
dried and powdered.
Intake of this
powder in normal
dosage treats
respiratory,
digestive and
urinary tract
complaints.
Thippali in Other
Languages
Gujarati:
Lindi pipar (roots
are known as
Ganthoda)
Marathi:
Pippali
Bengali:
Pipul
Kannada:
Hippali
Tamil &
Malayalam:
Tippali
Hindi Name :
Pepper
Sanskrit Name :
Pippali
Uses & Benefits of
Thippali
Thippali helps in
expelling out the
mucus accumulated in
the respiratory
tract.
It strengthens the
nervous system,
improves the
gastrointestinal
condition and
normalizes the
peristaltic
movements.
The herb serves as
a good digestive
agent.
Its oil and paste
is applied on wounds
and skin-related
ailments.
Thippali helps in
suppressing pain and
reducing
inflammation.
The herb helps
maintain the
normalcy of the
digestive tract and
tones up the urinary
tract.
Its fruits are
used for respiratory
tract diseases like
cough, bronchitis
and asthma.
It benefits in
anorexia,
indigestion,
flatulence,
abdominal pain,
hyperacidity, piles,
paralysis of the
tongue, diarrhea,
cholera, chronic
malaria, viral
hepatitis, diseases
of the spleen and
tumors.
It is given with amalaki, to treat
anemia.
The decoction of
the plant is used in
sciatica and hemiplegia.
The herb is mixed
with honey to
control hiccups.
Thippali is used
as an aphrodisiac,
since it boosts the
reproductive system.
It is used as a
sedative in insomnia
and epilepsy.
The infusion of
the herb’s root is
used after
childbirth, to
induce the expulsion
of the placenta.
Medicinal and
pharmacological
activities
Immunomodulatory
activity:
Tests such as
haemagglutination
titre (HA),
macrophage migration
index (MMI) and
phagocytic indeJ
(PI) in mice have
demonstrated the
immunostimulatory
action of Thippali
fruits to be both
specific and
non-specific. The
effect was more
prominent at lower
doses (225 mg/kg)
and was marginally
reduced when the
dose was increased,"
In another study, it
was found to offer
protection against
externally induced
stress,' A famous
Ayurvedic
preparation
containing Thippali,
Pippali Rasayana,
was tested in mice
infected with
Giardia lamblia and
found to produce
significant
activation of macro
phages, as shown by
an increased MMI and
phagocytic activity.
Stimulant
effects:
Isolated piperine
showed a central
stimulant action in
frogs, mice, rats
and dogs and
increased the
hypnotic response in
mice. It antagonised
respiratory
depression induced
by morphine or
pentobarbitone in
anaesthetised dogs
anda petroleum ether
extract of the
fruits antagonised
morphine-induced
respiratory
depression in mice,
A comparative study
conducted with
piperine and
nalorphine,for
effects against
morphine-induced
respiratory
depression and
analgesia, found
that both reversed
respiratory
depression but,
unlike nalorphine,
piperine did not
antagonise
morphine-induced
analgesia in rats,
Antiasthmatic
activity:
Studies have been
carried out to
validate the
traditional claims
of Ayurveda for
antiasthmatic
activity of Thippali.
An extract of the
fruits in milk
reduced passive
cutaneous
anaphylaxis in rats
and protected guinea
pigs against
antigen-induced
bronchospasm.
Bio-availability
enhancement:
Piperine has
been shown to
enhance the
bio-availability of
structurally and
therapeutically
diverse drugs,
possibly by
modulating membrane
dynamics, due to its
easy partitioning
and increasing
permeability.The
effect of Trikatu',
a compound Ayurvedic
preparation
containing Thippali
as one of the major
ingredients, was
tested in
combination with
other drugs. The
study reported that
Trikatu' increased
their
bio-availability
either by promoting
rapid absorption
from the
gastrointestinal
tract or by
protecting the drug
from being
metabolised during
its first passage
through the liver
after being
absorbed, or by
combination of both
mechanisms.
Hepatoprotective
activity:
Piperine was
evaluated and found
to exert significant
protection against
tertiary butyl
hydroperoxide and
carbon
tetrachlorideinduced
hepatotoxicity, by
reducing both in
vitro and in vivo
lipid peroxidation.
A fruit extract was
assessed in rodents
for its
hepatoprotective
action against
CCL,induced acute,
chronic and
reversible damage
and chronic
irreversible damage,
using morphological,
biochemical and
histopathological
assessment
parameters. The
extract improves the
regeneration process
by restricting
fibrosis, but
offered no
protection against
acute damage or
against cirrhotic
changes.
Hypocholesterolaemic
activity:
Methyl piperine
significantly
inhibited the
elevation
of total serum
cholesterol, and the
total cholesterol to
HDL-cholesterol
ratio, in rats fed
with a high
cholesterol diet.
The unsaponifiable
fraction of the oil
of Thippali also
significantly
decreased total
serum cholesterol
and hepatic
cholesterol in
hypercholesterolaemic
mice.
Antiinflammatory
activity:
A marked
antiinflammatory
activity of a
decoction of P.
longum fruits has
been reported using
carrageenan-induced
rat oedema.
Antiamoebic
activity:
The fruits were
tested for their
efficacy against
Entamoeba
histolytica in vitro
and experimental
caecal amoebiasis in
vivo. Both the
ethanolic extract
and isolated
piperine produced an
improvement of 90%
and 40%
respectively, in
rats with caecal
amoebiasis.
Antibacterial
activity:
The essential oil of
P. longum showed
antibacterial action
against a number of
bacterial
strains32,33
although a 50%
ethanolic extract of
the fruits did not
show any effect.3'
Piperlonguminine was
found to have potent
activity against
Bacillus subtilis
while piperine was
more effective
against
Staphylococcus
aureus.
The oil contains:
Piperine
Pipalartine
Piplasterol
Sesamin
Quality Assurance
As we believe in
providing quality
products that are
close to nature, we
conduct various
stringent quality
tests under the
supervision of the
experts. These tests
are performed with
due care from the
very initial stage
of procurement of
the products to the
final stage of
delivery to the end
users.